FASCINATION ABOUT CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most not long ago, it's been identified that conolidine and the above derivatives act to the atypical chemokine receptor three (ACKR3. Expressed in identical regions as classical opioid receptors, it binds to a wide array of endogenous opioids. Unlike most opioid receptors, this receptor acts like a scavenger and isn't going to activate a next mess